- Education, Portsmouth
- Educational Facilities, Portsmouth
- Educational, Philanthropic & Research Foundations, Portsmouth
- Educators, Portsmouth
- Electric Contractors Marine, Portsmouth
- Electric Motor Repair & Service, Portsmouth
- Electric Motors & Generators , Portsmouth
- Electrical Control Systems & Materials, Portsmouth
- Electrical Supplies, Parts & Equipment, Portsmouth - Wholesale & Manufacturers
- Electricians, Portsmouth - Electrical Contractors
- Electronic Games Manufacturers, Portsmouth
- Electronics Components, Portsmouth
- Electronics Manufacturers, Portsmouth
- Electronics Repair & Maintenance , Portsmouth
- Electronics Stores, Portsmouth
- Elementary Schools, Portsmouth
- Embroidery, Portsmouth
- Emergency Services, Portsmouth
- Emergency Victim Services, Portsmouth
- Employment Agencies, Portsmouth - Staffing Agencies
- Employment Assistance, Portsmouth
- Employment Services, Portsmouth
- Engine Rebuild, Repair & Exchange, Portsmouth
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- Engineer & Architect Services, Portsmouth - Engineering & Architecture Service
- Engineering Consultants, Portsmouth - Consulting Engineers
- Engineers - Water & Piping, Portsmouth - Water Supplies
- Engineers Industrial, Portsmouth
- Engraving & Platemaking, Portsmouth
- Engraving - Wood, Plastic, Jewelry, Etc, Portsmouth - Engraver
- Entertainers & Groups, Portsmouth
- Entertainment & Recreation, Portsmouth
- Entertainment Equipment & Supplies, Portsmouth
- Environmental Conservation & Ecological Services, Portsmouth - Ecosystem Services
- Environmental Groups, Portsmouth
- Environmental Products, Portsmouth
- Environmental Services, Portsmouth
- Environmental Services Monitoring, Portsmouth
- Episcopal Churches, Portsmouth
- Ethnic Goods & Products Stores, Portsmouth
- Ethnic Restaurants, Portsmouth
- European Cuisine, Portsmouth
- Evangelical Church, Portsmouth
- Exercise Equipment Repair & Service, Portsmouth
- Exercise Equipment Stores, Portsmouth - Fitness & Gym Equipment
- Exporters, Portsmouth
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