- Dairy Farms, South Boston
- Dairy Products - Wholesale & Retail, South Boston
- Dance Companies, South Boston
- Day Spas, South Boston
- Delicatessen Grocers, South Boston
- Delicatessen Restaurants, South Boston
- Deliverance Church, South Boston
- Dentists, South Boston
- Department Stores, South Boston
- Dermatologists, South Boston - Skin Doctors, Physicians & Surgeons (Dermatology)
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- Dimension Stone Products, South Boston
- Disability And Social Security Attorneys & Lawyers, South Boston
- Discount Stores, South Boston - Clothing, Grocery, Furniture, Etc
- Disease, Handicap & Disability Services, Organizations & Groups, South Boston
- Doctors, Physicians & Surgeons, South Boston
- Donuts, South Boston
- Drinking Establishments, South Boston
- Drug Screening Services, South Boston
- Dry Cleaning & Laundry, South Boston - Dry Cleaners
- Drywall, Insulation & Plaster Contractors, South Boston - Installation & Repair Services
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